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NP Board Prep

WHNP-BCNational Certification Corporation (NCC) · Women’s health

WHNP practice questions across the 2026 outline

Facts read from nccwebsite.org · last checked Nov 7, 2026

These 60 questions touch every area of NCC's 2026 outline, most of them gynecology and obstetrics. Each has three options, as on NCC's exam, and each option is explained after you pick.

Figure 1.Test content outline drawn to scale: each run is one domain’s weight

2026 guide · checked Nov 7, 2026
  1. I. Gynecologic and Reproductive Health33%
  2. II. Obstetrics29%
  3. III. Primary Care13%
  4. IV. Assessment, Diagnostic Testing and Interpretation12%
  5. V. Pharmacology10%
  6. VI. Professional Practice Issues3%

Composition of this set

Gynecology (outline 33%, split between disorders and contraception) and obstetrics (29%) take most of the set. The rest comes from assessment (12%), pharmacology (10%), women's primary care (13%) and professional issues (3%). The set leans further toward gynecology and obstetrics than the outline does and carries few primary care items; for primary care, add that page's own set. The area chips above the questions show the exact count for each.

None of these items repeats a question on the area pages, so the set works as a fresh check after studying them.

60 questions across six areas

0 / 60 answered60 questions

Tap an option: why each one is right or wrong appears under it.

Pregnancy complications and postpartum

A patient with a prior spontaneous preterm birth at 30 weeks has a transvaginal cervical length of 18 mm at 20 weeks. The most appropriate management is

  1. With a prior spontaneous preterm birth before 34 weeks and a cervical length under 25 mm before 24 weeks, ACOG recommends considering cerclage.
  2. Bed rest and activity restriction do not prevent preterm birth and raise thrombosis and deconditioning risk.
  3. Repeating the scan delays treatment once the cervix is already below 25 mm in a patient with prior preterm birth.

Item 422345 · Flag an error

Primary Care · 13%

A woman whose previous pregnancy was affected by a neural tube defect is planning to conceive. She should begin folic acid at least 1 month before conception at a daily dose of

  1. After a pregnancy affected by a neural tube defect, folic acid 4 mg daily is started at least 1 month before conception and continued through the first trimester.
  2. 0.4 mg is the usual dose for all women who could become pregnant; it is too low after a prior affected pregnancy.
  3. 1 mg is above the standard dose but still well below the 4 mg advised after a prior neural tube defect.

Item 422361 · Flag an error

Gynecologic disorders

A 37-year-old wants to know her ovarian reserve before deciding when to try to conceive. Which test can be drawn on any day of the menstrual cycle?

  1. A mid-luteal progesterone confirms ovulation in that cycle; it says nothing about ovarian reserve.
  2. AMH comes from small growing follicles and stays fairly stable through the cycle, so it can be drawn on any day to estimate ovarian reserve.
  3. FSH must be timed to the early follicular phase and varies between cycles, so it cannot be drawn on any day.

Item 422374 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

At 30 weeks, a nonstress test shows two fetal heart rate accelerations peaking 10 bpm above baseline and lasting 10 seconds within 20 minutes. The nurse practitioner should interpret the test as

  1. Extending the test fits a tracing that fails the criteria; calling it nonreactive applies the 15 bpm by 15 second rule meant for 32 weeks and later.
  2. Before 32 weeks an NST is reactive with two accelerations of at least 10 bpm lasting at least 10 seconds within 20 minutes, so this tracing at 30 weeks is reassuring.
  3. Equivocal is a biophysical profile category, not an NST result, and the tracing already meets the preterm criteria.

Item 422393 · Flag an error

Primary Care · 13%

The USPSTF recommends screening for intimate partner violence in

  1. USPSTF (2025) recommends screening women of reproductive age, including pregnant and postpartum women, for intimate partner violence and referring those who screen positive to ongoing support services.
  2. Limiting screening to pregnancy misses most women at risk; the recommendation covers all women of reproductive age, including but not limited to pregnant and postpartum women.
  3. For caregiver abuse of older or vulnerable adults USPSTF found the evidence insufficient (I statement), so universal screening of all adults is not the recommendation.

Item 422474 · Flag an error

Gynecologic disorders

A patient at 20 weeks' gestation has several small external genital warts that cause discomfort. The most appropriate treatment is

  1. In pregnancy, external genital warts are treated with clinician-applied options such as trichloroacetic acid or cryotherapy (CDC 2021).
  2. Imiquimod has limited safety data in pregnancy and is avoided, even though harm has not been shown.
  3. Podophyllin resin is contraindicated in pregnancy and has been dropped from CDC wart regimens because of systemic toxicity and inconsistent preparations.

Item 422494 · Flag an error

Contraception and fertility

A patient using a cervical mucus fertility awareness method notes clear, slippery, stretchy mucus. The nurse practitioner should explain that this means

  1. Fertile-type mucus appears mid-cycle before ovulation; menses follow about 2 weeks later, not within days.
  2. Rising estrogen before ovulation produces clear, slippery, stretchy mucus that helps sperm survive, so these are the fertile days just before ovulation.
  3. Progesterone after ovulation makes mucus thick, scant and sticky, the opposite of what she sees.

Item 422496 · Flag an error

Contraception and fertility

A 19-year-old taking combined oral contraceptives has a red, velvety area surrounding the external os. There is no discharge or contact bleeding, and gonorrhea and chlamydia NAATs are negative. The nurse practitioner should

  1. Cervical cytology starts at age 21, so screening a 19-year-old for a benign finding is not indicated.
  2. A red, velvety ring around the os in a young woman on combined pills is cervical ectropion, columnar epithelium on the ectocervix that needs no treatment once infection is excluded.
  3. Colposcopy is for abnormal screening results or a suspicious lesion; ectropion with negative tests is a normal variant.

Item 422501 · Flag an error

Professional Practice Issues · 3%

A patient's gonorrhea NAAT is positive, and she asks that no one else be told. Regarding reporting of the case, the nurse practitioner

  1. Gonorrhea is nationally notifiable, so the clinician must report it to the health department whatever the patient's wishes; the report is confidential.
  2. Treatment does not cancel the reporting duty; surveillance counts every diagnosed case.
  3. Public health reporting is a legal requirement that does not depend on consent, and HIPAA permits the disclosure.

Item 422538 · Flag an error

Pharmacology · 10%

A woman at 12 weeks' gestation has moderate inflammatory acne. The most appropriate treatment is

  1. Topical retinoids are generally avoided in pregnancy because of limited safety data and the known teratogenicity of oral retinoids.
  2. Azelaic acid, along with topical benzoyl peroxide or clindamycin, is considered safe for acne in pregnancy.
  3. Isotretinoin is a potent teratogen and is contraindicated in pregnancy under the iPLEDGE program.

Item 422552 · Flag an error

Gynecologic disorders

An 18-year-old with primary amenorrhea has normal breast development and a blind-ending vaginal pouch; ultrasound shows no uterus. Which test best distinguishes Müllerian agenesis from androgen insensitivity syndrome?

  1. A karyotype separates the two: Müllerian agenesis is 46,XX with normal ovaries, while androgen insensitivity is 46,XY with testes that need management.
  2. MRI shows the absent uterus in both and can locate gonads, but it does not establish chromosomal sex the way a karyotype does.
  3. Estradiol is normal or near-normal in both conditions, since ovaries in MRKH and testes in AIS (by aromatization) both supply estrogen.

Item 422619 · Flag an error

Pregnancy complications and postpartum

After a stillbirth at 34 weeks' gestation, which evaluation has the highest yield for determining the cause?

  1. Examination of the placenta, cord and membranes, along with fetal autopsy, gives the highest yield for finding the cause of a stillbirth.
  2. Antithyroid antibodies do not explain a stillbirth and are not part of the recommended evaluation.
  3. TORCH panels are low yield and no longer recommended; targeted testing such as syphilis serology and parvovirus studies is used instead.

Item 422657 · Flag an error

Pharmacology · 10%

A 29-year-old woman taking a combined oral contraceptive develops new migraines preceded by visual aura. The nurse practitioner should

  1. No estrogen dose is considered safe with aura; lowering the dose keeps the stroke risk.
  2. The patch still delivers estrogen, so it carries the same contraindication with aura.
  3. New migraine with aura on a combined pill makes estrogen US MEC category 4 because of stroke risk, so she should stop it and use a progestin-only or nonhormonal method.

Item 422669 · Flag an error

Contraception and fertility

A cisgender female couple wants one partner to provide the eggs and the other partner to carry the pregnancy. The nurse practitioner should explain that this is done through

  1. In reciprocal IVF one partner's oocytes are fertilized with donor sperm and the embryo is transferred to the other partner's uterus, so both take part biologically.
  2. Insemination uses the eggs and uterus of the same partner, so it cannot split egg provider and carrier.
  3. Surrogacy uses a third person to carry the pregnancy; here one of the partners will carry it.

Item 422711 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

A nonpregnant 23-year-old was treated with doxycycline for chlamydia 3 weeks ago and has no symptoms. The nurse practitioner should retest her

  1. A test of cure is not needed after doxycycline in a nonpregnant patient, and a NAAT within 4 weeks can detect dead organisms and give a false positive.
  2. Most chlamydial reinfections are asymptomatic, so waiting for symptoms misses them; retesting is planned at 3 months.
  3. Because reinfection is common, CDC advises retesting women about 3 months after chlamydia treatment, or at the next visit within 12 months.

Item 422725 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

A 49-year-old with hot flashes has not had a period for 7 months. The nurse practitioner should explain that she

  1. FSH fluctuates widely during the transition and does not confirm menopause in a woman over 45 with typical symptoms; the diagnosis is clinical.
  2. Menopause is diagnosed retrospectively after 12 consecutive months of amenorrhea; 7 months is not enough.
  3. Under STRAW+10, 60 days or more of amenorrhea marks the late menopausal transition, and menopause is defined only after 12 months without a period.

Item 422730 · Flag an error

Pharmacology · 10%

A woman is prescribed doxycycline 100 mg twice daily for 7 days for chlamydia. The nurse practitioner should counsel her to

  1. The 72-hour alcohol warning was traditionally given for metronidazole or tinidazole, not for doxycycline.
  2. Doxycycline causes photosensitivity, so sunscreen and avoiding strong sun are advised during the 7-day course.
  3. Orange urine is a known effect of rifampin or phenazopyridine, not doxycycline.

Item 422743 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

A 32-year-old has had 6 months of amenorrhea with hot flashes. Pregnancy test, TSH, and prolactin are normal. Which result confirms primary ovarian insufficiency?

  1. An FSH just above 10 IU/L suggests diminished reserve but is well below the 25 IU/L threshold for primary ovarian insufficiency.
  2. Under the 2024 ESHRE/ASRM guideline, a single FSH above 25 IU/L in a woman under 40 with 4 or more months of oligo- or amenorrhea confirms primary ovarian insufficiency; a repeat FSH or AMH is needed only when the picture is uncertain.
  3. A low AMH supports the diagnosis only when it is uncertain; on its own it is not the diagnostic criterion, which rests on FSH.

Item 422821 · Flag an error

Gynecologic disorders

A 26-year-old has had pain at vaginal entry with intercourse and tampon use for 1 year. The vulva looks normal, cultures are negative, and light cotton-swab touch at the vaginal opening causes sharp pain. The most likely diagnosis is

  1. Vaginismus is involuntary pelvic floor muscle tightening that prevents penetration; the cotton-swab test localizes pain to the vestibular mucosa rather than to muscle spasm.
  2. Lichen sclerosus shows white, thinned skin and architectural changes; a normal-appearing vulva argues against it.
  3. Entry pain with intercourse and tampons for months, a normal-looking vulva, negative cultures and sharp pain on light cotton-swab touch at the vestibule define provoked vestibulodynia.

Item 422826 · Flag an error

Pharmacology · 10%

Before prescribing oral micronized progesterone as part of hormone therapy, the nurse practitioner should ask about an allergy to

  1. Latex allergy matters for condoms and some medical devices, not for an oral progesterone capsule.
  2. Oral micronized progesterone capsules (Prometrium) are formulated in peanut oil, so a peanut allergy is a contraindication to that product.
  3. Micronized progesterone has no sulfonamide group, so a sulfa allergy does not affect it.

Item 422840 · Flag an error

Pharmacology · 10%

A woman who weighs 95 kg asks about the norelgestromin–ethinyl estradiol patch. The nurse practitioner should counsel her that this patch

  1. The norelgestromin–ethinyl estradiol patch label warns of reduced efficacy in women weighing 198 lb (90 kg) or more, which applies to her at 95 kg.
  2. Weight above 90 kg is a caution about efficacy on the label, not a contraindication.
  3. The patch gives about 60 % higher estrogen exposure than a 35-mcg pill, which is why its VTE warning is stronger.

Item 422846 · Flag an error

Pregnancy complications and postpartum

A woman with a confirmed early pregnancy loss at 8 weeks chooses medical management. The most effective regimen is

  1. The first-trimester uterus has few oxytocin receptors, so oxytocin does not work for early pregnancy loss.
  2. For early pregnancy loss, mifepristone 200 mg followed 24 hours later by misoprostol 800 mcg vaginally completes expulsion more often than misoprostol alone.
  3. A single 200-mcg oral dose is too low; misoprostol alone uses 800 mcg vaginally and is less effective than the combined regimen.

Item 422847 · Flag an error

Prenatal care

A preschool teacher planning pregnancy asks how to reduce her risk of cytomegalovirus infection. The nurse practitioner should recommend

  1. Routine serial CMV serology is not recommended because results are hard to interpret and do not prevent infection.
  2. There is no licensed CMV vaccine; recommending one confuses CMV with rubella or varicella prevention.
  3. No CMV vaccine exists, so prevention relies on handwashing after contact with young children's saliva or urine and not sharing utensils or food.

Item 422865 · Flag an error

Gynecologic disorders

A 28-year-old with severe dysmenorrhea, deep dyspareunia, and uterosacral nodularity on examination does not want pregnancy now. The most appropriate initial management is

  1. Suspected endometriosis in a patient not seeking pregnancy is treated empirically first with NSAIDs and hormonal suppression such as a combined hormonal contraceptive; surgery is not needed to start treatment.
  2. Danazol works but causes androgenic effects such as acne, hirsutism and voice change, so it is not used as initial therapy.
  3. Laparoscopy is reserved for failure of medical therapy, an uncertain diagnosis or a pelvic mass; requiring it first delays relief and adds surgical risk.

Item 422893 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

A von Willebrand panel is ordered for a 24-year-old with heavy menstrual bleeding since menarche. Which factor is most likely to produce a falsely normal result?

  1. Estrogen raises von Willebrand factor and factor VIII, so testing on a combined pill can mask von Willebrand disease; ideally samples are drawn off estrogen or repeated.
  2. Early-cycle testing (days 1 to 4) is when von Willebrand factor is lowest, so it improves rather than hides detection.
  3. Fasting does not change von Willebrand factor levels; stress, exercise, pregnancy, inflammation and estrogen do.

Item 422935 · Flag an error

Prenatal care

In the second half of pregnancy, the principal action of human placental lactogen (hPL) is to

  1. Human placental lactogen rises through the second half of pregnancy and opposes insulin, shifting glucose toward the fetus; this contra-insulin effect is why glucose tolerance worsens as pregnancy advances.
  2. Softening of the pelvic joints and ligaments is attributed mainly to relaxin and progesterone, not to human placental lactogen.
  3. Keeping the corpus luteum making progesterone in early pregnancy is the role of hCG, not of human placental lactogen.

Item 422961 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

Which test is part of the basic infertility evaluation for a heterosexual couple?

  1. Laparoscopy is reserved for specific indications such as suspected endometriosis or abnormal HSG; it is not part of the basic work-up.
  2. Hysterosalpingography assesses tubal patency and the uterine cavity and is part of the basic infertility evaluation, with ovulation testing and a semen analysis.
  3. The postcoital test has poor reproducibility and does not predict pregnancy, so it is no longer recommended.

Item 422970 · Flag an error

Pregnancy complications and postpartum

After uterine evacuation of a complete hydatidiform mole, the nurse practitioner should counsel the patient to

  1. After a molar evacuation, reliable contraception is needed throughout hCG follow-up, because a new pregnancy would raise hCG and hide gestational trophoblastic neoplasia; hormonal methods are safe and preferred.
  2. Hormonal contraception does not raise the risk of postmolar neoplasia; avoiding it reflects an outdated concern and leaves less effective options.
  3. Conception is deferred until follow-up after the first normal hCG is complete (for a complete mole, at least one further normal monthly value), so that any later rise can be interpreted.

Item 422983 · Flag an error

Primary Care · 13%

A 45-year-old woman asks whether her pregnancy history affects her heart disease risk. Which history is recognized as a risk enhancer for cardiovascular disease?

  1. Placenta previa is a placental location problem and has not been linked to later cardiovascular disease.
  2. ACC/AHA list preeclampsia and other hypertensive disorders of pregnancy as risk enhancers for atherosclerotic cardiovascular disease in women.
  3. Breech presentation is a fetal position and is not a cardiovascular risk enhancer.

Item 422986 · Flag an error

Prenatal care

A pregnant patient drinks three 12-oz cups of brewed coffee a day, about 140 mg of caffeine each. The nurse practitioner should advise

  1. ACOG advises keeping caffeine below 200 mg a day in pregnancy, which for her coffee at about 140 mg a cup means roughly one cup.
  2. Her current intake of about 420 mg a day is more than twice the recommended limit.
  3. Two cups would be about 280 mg, above the 200 mg daily limit.

Item 423014 · Flag an error

Pregnancy complications and postpartum

At 3 months postpartum, a patient has palpitations, anxiety and weight loss. TSH is low, free T4 is high, TSH-receptor antibodies are negative and there is no thyroid bruit. The most appropriate treatment is

  1. Radioactive iodine treats Graves disease or toxic nodules, is contraindicated while breastfeeding, and is not used for a self-limited thyroiditis.
  2. Antithyroid drugs block new hormone synthesis and do not help when hormone leaks from an inflamed gland; they are used for Graves disease.
  3. Thyrotoxicosis at 3 months postpartum with negative TSH-receptor antibodies is the hyperthyroid phase of postpartum thyroiditis, a painless destructive process treated with a beta-blocker for symptoms.

Item 423018 · Flag an error

Prenatal care

At 34 weeks, a healthy patient's liver panel shows an alkaline phosphatase 3 times the nonpregnant upper limit, with normal AST, ALT and bilirubin. This finding is most consistent with

  1. The placenta makes alkaline phosphatase, so levels 2 to 4 times normal in the third trimester with normal transaminases and bilirubin are an expected placental effect.
  2. Cholestasis causes itching and a rise in bile acids, often with elevated transaminases; an isolated alkaline phosphatase rise in a healthy patient does not suggest it.
  3. AFLP presents with malaise, vomiting, jaundice, hypoglycemia and coagulopathy; normal transaminases and bilirubin rule it out.

Item 423048 · Flag an error

Pregnancy complications and postpartum

After a spontaneous abortion at 9 weeks, a patient asks what caused it. The nurse practitioner should explain that the leading cause of first-trimester loss is

  1. Inherited thrombophilias are not proven causes of early loss, and testing for them is not recommended after a miscarriage.
  2. About half of first-trimester losses are caused by fetal chromosomal abnormalities, most often autosomal trisomies.
  3. Uterine anomalies such as a septum account for a small share of losses and are evaluated only after recurrent miscarriage.

Item 423051 · Flag an error

Prenatal care

At 35 weeks, a patient reports irregular, painless abdominal tightening that eases when she changes activity or rests, with no bleeding or fluid leakage. These are most consistent with

  1. Preterm labor brings regular, increasingly frequent contractions that do not stop with rest and cause cervical change.
  2. Round ligament pain is a brief sharp groin or lower abdominal pain with movement, not generalized tightening of the uterus.
  3. Irregular, painless tightening that eases with rest or a change in activity, without bleeding or leakage, is typical of Braxton Hicks contractions.

Item 423053 · Flag an error

Pregnancy complications and postpartum

A patient at 37 weeks reports a gush of fluid. Which sterile speculum finding confirms rupture of membranes?

  1. Amniotic fluid has a pH of about 7.0 to 7.5; a pH of 4.2 is normal vaginal acidity and argues against rupture.
  2. Amniotic fluid dried on a slide forms a fern pattern under the microscope, which supports rupture of membranes along with pooling and a positive nitrazine test.
  3. Nitrazine paper turns blue with alkaline amniotic fluid; staying yellow means an acidic pH.

Item 423054 · Flag an error

Prenatal care

Which antenatal measure reduces tears that need suturing at a first vaginal birth?

  1. Pelvic floor exercises help prevent incontinence but have not been shown to reduce perineal tears at birth.
  2. Antenatal digital perineal massage from about 34 or 35 weeks reduces trauma that needs suturing and later perineal pain, mainly in nulliparous patients.
  3. Sitz baths soothe perineal discomfort after birth; they do not prepare tissue or prevent tears.

Item 423065 · Flag an error

Contraception and fertility

A patient plans to have a levonorgestrel IUD placed within 10 minutes after delivery of the placenta. Compared with placement at 6 weeks postpartum, she should be counseled that immediate placement has a higher rate of

  1. IUDs placed within 10 minutes of placental delivery are safe and effective but are expelled more often, around 10 to 25 %, than those placed at 6 weeks.
  2. Levonorgestrel IUDs placed after birth have not been shown to reduce milk supply or breastfeeding duration.
  3. Immediate postplacental placement does not increase the risk of pelvic infection compared with interval placement.

Item 423073 · Flag an error

Prenatal care

Cell-free DNA screening at 11 weeks returns a high-risk result for trisomy 21. The most appropriate next step is to

  1. Treating a screen as a diagnosis can lead to irreversible decisions based on a false positive.
  2. Cell-free DNA is a screening test with false positives from placental mosaicism, so a high-risk result is followed by diagnostic CVS or amniocentesis before any decision.
  3. Repeating a screening test cannot confirm the diagnosis; a second screen only delays diagnostic testing.

Item 423088 · Flag an error

Prenatal care

A patient with a prepregnancy BMI of 23 kg/m² and a singleton pregnancy should be counseled to gain a total of

  1. For a normal prepregnancy BMI of 18.5 to 24.9 kg/m², the IOM recommends a total gain of 25 to 35 lb (11.5 to 16 kg) in a singleton pregnancy.
  2. 11 to 20 lb is the range for women with obesity (BMI 30 or more).
  3. 28 to 40 lb is the range for underweight women with a BMI below 18.5.

Item 423092 · Flag an error

Pregnancy complications and postpartum

At 34 weeks, a patient has blood pressures of 146/94 and 150/96 mm Hg 4 hours apart, a urine protein/creatinine ratio of 0.4, platelets 180,000/mm³, normal liver enzymes and no symptoms. The most likely diagnosis is

  1. New BP of 140/90 mm Hg or higher twice at least 4 hours apart after 20 weeks with a protein/creatinine ratio of 0.3 or more is preeclampsia; no severe-range BP, lab changes or symptoms means without severe features.
  2. Severe features require BP of 160/110 mm Hg or higher, platelets under 100,000, abnormal liver or renal values, pulmonary edema or new symptoms, and none are present.
  3. Gestational hypertension is new hypertension without proteinuria or end-organ signs; a protein/creatinine ratio of 0.4 meets the proteinuria criterion.

Item 423101 · Flag an error

Gynecologic disorders

Under CDC guidance, doxycycline post-exposure prophylaxis (doxy-PEP) should be offered to which patient with a bacterial STI in the past 12 months?

  1. In the trial of cisgender women doxy-PEP did not reduce bacterial STIs, so CDC does not make a recommendation for this group.
  2. Cisgender heterosexual men were not studied in the trials, and the recommendation does not include them.
  3. CDC's 2024 guidance recommends offering doxycycline 200 mg within 72 hours of condomless sex to men who have sex with men and transgender women who had syphilis, gonorrhea or chlamydia in the past 12 months.

Item 423110 · Flag an error

Contraception and fertility

A 25-year-old who uses a wheelchair and has limited mobility requests menstrual suppression. Which method is LEAST appropriate as first choice because of her risk profile?

  1. The implant has no estrogen-related clot risk and no bone loss; its main drawback is unpredictable bleeding, not safety.
  2. In a woman with limited mobility, DMPA adds bone density loss to a skeleton already at risk from immobility, and it can cause weight gain that makes transfers harder, so it is a poor first choice.
  3. The 52-mg levonorgestrel IUD suppresses menses in many users without estrogen or bone effects, which makes it a good first option.

Item 423117 · Flag an error

Contraception and fertility

A patient requests permanent contraception at her scheduled cesarean. Which procedure also provides the greatest reduction in ovarian cancer risk?

  1. Clips occlude the tubes but leave the fimbriae in place, so the cancer risk reduction is smaller than with complete removal.
  2. Many high-grade serous ovarian cancers start in the tubes, so removing both tubes completely gives permanent contraception and the greatest reduction in ovarian cancer risk.
  3. Cauterizing a segment blocks the tube but leaves the fimbriated end, giving less ovarian cancer protection than salpingectomy.

Item 423132 · Flag an error

Prenatal care

The standard betamethasone course for fetal lung maturity is

  1. The alternative course is dexamethasone 6 mg IM every 12 hours for four doses; an IV every-6-hour schedule mixes up the regimens and is not used.
  2. Oral corticosteroids are not used for fetal lung maturity, and a 7-day course has no role.
  3. Antenatal betamethasone is given as 12 mg intramuscularly in two doses 24 hours apart; the alternative is dexamethasone 6 mg IM every 12 hours for four doses.

Item 423146 · Flag an error

Contraception and fertility

A 30-year-old asks how her choices affect her risk of endometrial cancer. Which factor lowers that risk?

  1. Combined pills lower endometrial cancer risk by about 30 % or more, and the protection lasts for decades after stopping.
  2. Late menopause lengthens estrogen exposure and raises endometrial cancer risk.
  3. Nulliparity increases endometrial cancer risk because of more years of unopposed ovulatory cycles.

Item 423153 · Flag an error

Prenatal care

At 28 weeks, an asymptomatic patient has an ultrasound that incidentally shows mild right hydronephrosis and hydroureter. Urinalysis and serum creatinine are normal. This finding most likely represents

  1. Pyelonephritis causes fever, flank pain and pyuria, none of which are present.
  2. An obstructing stone causes colicky flank pain and often hematuria; an asymptomatic patient with a normal urinalysis is unlikely to have one.
  3. Progesterone and compression of the ureter by the uterus cause right-predominant hydronephrosis in most pregnancies, and with normal urinalysis and creatinine it needs no treatment.

Item 423184 · Flag an error

Gynecologic disorders

A 22-year-old has painful vulvar ulcers, dysuria and tender inguinal nodes. This is her first episode, and HSV PCR is pending. The most appropriate treatment is

  1. The 3-day course treats recurrent episodes; a first episode is longer and more severe and needs 7 to 10 days.
  2. A first episode of genital herpes is treated for 7 to 10 days, for example valacyclovir 1 g twice daily, started on clinical grounds before PCR results return (CDC 2021).
  3. Topical acyclovir offers minimal benefit and is not recommended; oral therapy shortens a first episode.

Item 423237 · Flag an error

Prenatal care

At 7 weeks' gestation, a patient needs surgical removal of the corpus luteum. The nurse practitioner anticipates that she will need

  1. The corpus luteum supplies progesterone until the luteal–placental shift at about 8 to 10 weeks, so its removal at 7 weeks requires progesterone replacement until then.
  2. hCG supports the corpus luteum, which has been removed, so it cannot replace the missing progesterone.
  3. At 7 weeks the placenta does not yet make enough progesterone; without replacement the pregnancy is at risk of loss.

Item 423239 · Flag an error

Contraception and fertility

A 38-year-old man had a vasectomy today. He and his partner ask when they can stop using another contraceptive method. The nurse practitioner should advise

  1. A count of ejaculations was an older rule of thumb; clearance varies, and only a semen analysis confirms success.
  2. Sperm remain in the ducts after vasectomy, so another method is used until a semen analysis about 8 to 16 weeks later shows azoospermia or rare nonmotile sperm (AUA).
  3. Healing of the incision says nothing about sperm left in the vas, which can cause pregnancy for weeks.

Item 423240 · Flag an error

Contraception and fertility

A 24-year-old who identifies as asexual and has never had sexual contact wants a combined oral contraceptive for dysmenorrhea. Her cervical screening is up to date and her blood pressure is normal. The nurse practitioner should

  1. Combined pills need only a medical history and a blood pressure; she has never had sexual contact, so STI testing and a pelvic exam add nothing.
  2. A pelvic exam is not required before hormonal contraception and can be a barrier to care, especially for someone who has never had sexual contact.
  3. Routine lipid testing is not needed before starting combined pills in a healthy woman (US SPR).

Item 423243 · Flag an error

Contraception and fertility

A 46-year-old with irregular cycles and hot flashes has a single FSH of 32 mIU/mL. She asks whether she can stop contraception. The nurse practitioner should advise that

  1. FSH fluctuates from cycle to cycle in perimenopause, so one high value does not prove infertility.
  2. Six months of amenorrhea is not enough; ovulation can resume after long gaps, and the usual rule is 12 months after age 50.
  3. A single FSH in the perimenopausal range does not mean ovulation has stopped; contraception is advised until age 50 to 55 or 12 months without menses after age 50.

Item 423280 · Flag an error

Gynecologic disorders

A 38-year-old has chronic pelvic pain with urinary frequency and dyspareunia. Pain worsens as the bladder fills and eases after voiding. Urine cultures are repeatedly negative. The most likely diagnosis is

  1. Overactive bladder causes urgency and frequency, but not pain that rises with bladder filling and is relieved by voiding.
  2. Pain that builds as the bladder fills and eases after voiding, with frequency and repeatedly negative cultures, is typical of interstitial cystitis (bladder pain syndrome); first-line care is education, diet changes and pelvic floor therapy.
  3. A urethral diverticulum causes postvoid dribbling, dyspareunia and a tender anterior vaginal wall mass, not pain that builds with bladder filling and eases after voiding.

Item 423287 · Flag an error

Gynecologic disorders

A 45-year-old transgender man had a total hysterectomy with bilateral salpingo-oophorectomy 3 years ago and stopped testosterone 1 year ago because of cost. The greatest health concern is

  1. Vaginal cytology is not needed after total hysterectomy for benign disease with no history of high-grade dysplasia.
  2. After hysterectomy there is no endometrium, so hyperplasia is not a risk.
  3. With no ovaries and no testosterone he has no sex steroids, which leads to rapid bone loss, so restarting hormone therapy and assessing bone density are priorities.

Item 423319 · Flag an error

Assessment, Diagnostic Testing and Interpretation · 12%

Which cervical screening result in a 32-year-old warrants colposcopy regardless of cytology?

  1. HPV-negative ASC-US has a low immediate risk and returns to repeat HPV-based testing in 3 years, not colposcopy.
  2. Under ASCCP 2019, HPV 16 or 18 positivity carries enough immediate CIN 3+ risk to warrant colposcopy even when cytology is normal.
  3. Other high-risk HPV types with normal cytology are managed with repeat HPV-based testing in 1 year.

Item 423336 · Flag an error

Gynecologic disorders

A 34-year-old has vulvar itching and burning since switching to scented wipes and pads. There is vulvar erythema without discharge, and the wet mount and KOH are negative. The most appropriate initial management is

  1. Biopsy is for persistent or atypical lesions or failure of treatment; a clear irritant with a short history is managed first by avoidance.
  2. Fluconazole treats candidiasis, which a negative KOH makes unlikely; empiric antifungals for every vulvar itch delay the correct diagnosis.
  3. Vulvar burning after starting scented wipes and pads, with negative wet mount and KOH, points to irritant contact dermatitis, treated first by stopping the products and using bland emollients.

Item 423346 · Flag an error

Contraception and fertility

A 34-year-old had a levonorgestrel 52-mg IUD placed 2 years ago for contraception and asks how long it will protect her. The nurse practitioner should advise replacement at

  1. Five years was the original contraceptive label and remains the approved duration for treating heavy menstrual bleeding with Mirena.
  2. Ten years is the labeled duration of the copper T380A IUD, not a levonorgestrel device.
  3. Both 52-mg levonorgestrel IUDs (Mirena and Liletta) are FDA-approved for up to 8 years of contraception.

Item 423356 · Flag an error

Contraception and fertility

A 26-year-old asks about the lactic acid–citric acid–potassium bitartrate vaginal contraceptive gel. Which history makes this method a poor choice?

  1. Migraine with aura rules out estrogen, but the gel is hormone-free, so aura is not a reason to avoid it.
  2. The lactic acid, citric acid and potassium bitartrate gel raised the rate of urinary tract infection in trials and is not advised for women with recurrent UTIs.
  3. Prior DVT is a contraindication to estrogen methods, not to a nonhormonal vaginal gel.

Item 925741 · Flag an error

Contraception and fertility

The primary contraceptive mechanism of the copper IUD is

  1. Copper ions set up a sterile inflammatory reaction in the uterus and tubes that is toxic to sperm and ova, so fertilization is prevented; the copper IUD contains no hormone.
  2. Thickened cervical mucus is a main mechanism of the levonorgestrel IUD, which releases a progestin; the copper device has none.
  3. Neither IUD reliably suppresses ovulation; ovulation continues in most copper IUD users.

Item 925743 · Flag an error

Gynecologic disorders

A 55-year-old has vulvovaginal dryness, dyspareunia and three culture-proven UTIs this year. The most appropriate initial treatment is

  1. Low-dose vaginal estrogen treats genitourinary syndrome of menopause and reduces recurrent UTIs in postmenopausal women by restoring lactobacilli and a lower pH.
  2. Systemic hormone therapy is for vasomotor symptoms; for isolated genitourinary symptoms it adds systemic risk without better local effect.
  3. Antibiotic prophylaxis is a later step and promotes resistance; treating the atrophy first addresses the cause.

Item 925753 · Flag an error

Pregnancy complications and postpartum

Since a vaginal birth complicated by severe postpartum hemorrhage 6 weeks ago, a patient's milk has never come in. She now reports fatigue and cold intolerance. The most likely diagnosis is

  1. Postpartum thyroiditis can cause hypothyroid symptoms, but it does not stop milk from coming in after a hemorrhage.
  2. Anemia after hemorrhage explains fatigue but not failed lactation and cold intolerance from pituitary loss.
  3. Pituitary infarction after severe postpartum hemorrhage causes failure of lactation first, then hypothyroidism and adrenal insufficiency, which is Sheehan syndrome.

Item 925759 · Flag an error

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